Publications

2020

Chandler BC, Moubadder L, Ritter CL, Liu M, Cameron M, Wilder-Romans K, Zhang A, Pesch AM, Michmerhuizen AR, Hirsh N, Androsiglio M, Ward T, Olsen E, Niknafs YS, Merajver SD, Thomas DG, Brown PH, Lawrence TS, Nyati S, Pierce LJ, Chinnaiyan A, Speers C. TKK inhibition radiosensitizes basal-like breast cancer through impaired homologous. J Clin Inves. 2020 Jan 21. pii: 130435. doi: 10.1172/JCI130435. PMID: 31961339

Merrill NM, Lachacz EJ, Vandecan NM, Ulintz PJ, Bao L, Lloyd JP, Yates JA, Morikawa A, Merajver SD, Soellner MB. Molecular determinants of drug response in TNBC cell lines. Breast Cancer Res Treat. 2020 Jan. doi: 10.1007/s10549-019-05473-9. PMID: 31655920

2019

Newman LA, Jenkins B, Chen Y, Oppong JK, Adjei E, Jibril AS, Hoda S, Cheng E, Chitale D, Bensenhaver JM, Awuah B, Bekele M, Abebe E, Kyei I, Aitpillah F, Adinku M, Nathanson SD, Jackson L, Jiagge E, Merajver SD, Petersen LF, Proctor E, Gyan KK, Martini R, Kittles R, Davis MB. Hereditary Susceptibility for Triple Negative Breast Cancer Associated with Western Sub-Saharan African Ancestry: Results from an International Surgical Breast Cancer Collaborative. Ann Surg. 2019 Sep;270(3):484-492. doi: 10.1097/SLA. PMID: 31356281


Altemus MA, Goo LE, Little AC, Yates JA, Cheriyan HG, Wu ZF, Merjaver SD. Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes. PLoS One. 2019 Sept 19; 14(9):e0220973. doi: 10.1371/journal.pone.0220973. PMID: 31536495


Little AC, Pathanjeli P, Wu Z, Bao L, Goo LE, Yates JA, Oliver CR, Soellner MB, Merajver SD. IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling. Front. Oncol. 2019 May 31; 9:456. doi: 10.3389/fonc.2019.00456. PMID: 31214501


Schairer C, Hablas A, Eldein IAS, Gaafar R, Rais H, Mezlini A, Ayed FB, Ayoub WB, Benider A, Tahri A, Khouchani M, Aboulazm D, Karkouri M, Eissa S, Pfeiffer RM, Gadalla SM, Swain SM, Merajver SD, Brown LM, Soliman AS. Clinico-pathologic and mammographic characteristics of inflammatory and non-inflammatory breast cancer at six centers in North Africa. Breast Cancer Res Treat. 2019 Jul;176(2):407-417. doi: 10.1007/s10549-019-05237-5. Epub 2019 Apr 22. PMID: 31006821


Oliver CR, Altemus MA, Westerhof TM, Cheriyan H, Cheng X, Dziubinski M, Wu Z, Yates J, Morikawa A, Heth J, Castro MG, Leung BM, Takayama S, Merajver SD. A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche. Lab Chip. 2019 Mar 27;19(7):1162-1173. doi: 10.1039/c8lc01387j. PMID: 30810557


Chen W, Allen SG, Qian W, Peng Z, Han S, Li X, Sun Y, Fournier C, Bao L, Lam RHW, Merajver SD, Fu J. Biophysical Phenotyping and Modulation of ALDH+ Inflammatory Breast Cancer Stem-Like Cells. Small, 2019 February, doi: 10.1002/smll.201802891. PMID: 30632269


Merz L, Afriyie O, Jiagge E, Adjei E, Foltin SK, Ludwig ML, McHugh JB, Brenner JC, Merajver SD. Clinical characteristics, HIV status, and molecular biomarkers in squamous cell carcinoma of the conjunctiva in Ghana. Health Science Report, 2019 January, doi: 10.1002/hsr2.108. PMID: 30809594


Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince ME, McHugh JB, Donkor P, Merajver SD, Brenner JC. Correction: Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana. PLoS One, 2018 December, doi: 10.1371/journal.pone.0209696. PMID: 30566529

2018

Luo M, Shang L, Brooks MD, Jiagge E, Zhu Y, Buschhaus JM, Conley S, Fath MA, Davis A, Gheordunescu E, Wang Y, Harouaka R, Lozier A, Triner D, McDermott S, Merajver SD, Luker GD, Spitz DR, Wicha MS. Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. Cell Metab. 2018 Jul 3;28(1):69-86.e6. doi: 10.1016/j.cmet.2018.06.006.


Ko KP, Kim SJ, Huzarski T, Gronwald J, Lubinski J, Lynch HT, Armel S, Park SK, Karlan B, Singer CF, Neuhausen SL, Narod SA, Kotsopoulos J; Hereditary Breast Cancer Clinical Study Group. The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers. Int J Cancer. 2018 Jun 1;142(11):2263-2272. doi: 10.1002/ijc.31257. Epub 2018 Jan 25.


Jones T, Duquette D, Underhill M, Ming C, Mendelsohn-Victor KE, Anderson B, Milliron KJ, Copeland G, Janz NK, Northouse LL, Duffy SM, Merajver SD, Katapodi MC.

Surveillance for cancer recurrence in long-term young breast cancer survivors randomly selected from a statewide cancer registry. Breast Cancer Res Treat. 2018 May;169(1):141-152. doi: 10.1007/s10549-018-4674-5. Epub 2018 Jan 20


Rosselli-Murai LK, Yates JA, Yoshida S, Bourg K, Ho KKY, White M, Prisby J, Tan X, Altemus M, Bao L, Wu Z-F, Veatch SL, Swanson JA, Merajver SD, Liu AP. Loss of PTEN Promotes Formation of Signaling-Capable Clathrin-Coated Pits. J Cell Sci. 2018 Apr 26;131(8). pii: jcs208926. doi: 10.1242/jcs.208926.


Katapodi MC, Jung M, Schafenacker AM, Milliron KJ, Mendelsohn-Victor KE, Merajver SD, Northouse LL. Development of a Web-based Family Intervention for BRCA Carriers and Their Biological Relatives: Acceptability, Feasibility, and Usability Study. JMIR Cancer. 2018 Apr 13;4(1):e7. doi: 10.2196/cancer.9210.


Hadgu E, Seifu D, Tigneh W, Bokretsion Y, Bekele A, Abebe M, Sollie T, Merajver SD, Karlsson C, Karlsson MG. Breast cancer in Ethiopia: evidence for geographic difference in the distribution of molecular subtypes in Africa. BMC Womens Health. 2018 Feb 14;18(1):40. doi: 10.1186/s12905-018-0531-2.


2017

Thomas AS, Kidwell KM, Oppong JK, Adjei EK, Osei-Bonsu E, Boahene A, Jiggae E, Gyan K, Merajver SD. Breast Cancer in Ghana: Demonstrating the Need for Population-Based Cancer Registries in Low- and Middle-Income Countries. J Glob Oncol. 2017 Dec;3(6):765-772. doi: 10.1200/JGO.2016.006098. Epub 2017 Mar 27.


Aw Yong KM, Li Z, Merajver SD, Fu J. Tracking the tumor invasion front using long-term fluidic tumoroid culture. Sci Rep. 2017 Sep 7;7(1):10784. doi: 10.1038/s41598-017-10874-1.


Merajver S, Phadke S, Soellner M. Conquering the challenges of genotypic and phenotypic tumor heterogeneity to realize the promise of personalized cancer therapy: the role of academia. Trans Am Clin Climatol Assoc. 2017;128:169-179.


Aw Yong KM, Sun Y, Merajver SD, Fu J. Mechanotransduction-Induced Reversible Phenotypic Switching in Prostate Cancer Cells. Biophys J. 2017 Mar 28;112(6):1236-1245. doi: 10.1016/j.bpj.2017.02.012.


Le L, Schairer C, Hablas A, Meza J, Watanabe-Galloway S, Ramadan M, Merajver SD, Seifeldin IA, Soliman AS. Reliability of medical records in diagnosing inflammatory breast cancer in Egypt. BMC Res Notes. 2017 Mar 16;10(1):126. doi: 10.1186/s13104-017-2433-z.


Katapodi MC, Duquette D, Yang JJ, Mendelsohn-Victor K, Anderson B, Nikolaidis C, Mancewicz E, Northouse LL, Duffy S, Ronis D, Milliron KJ, Probst-Herbst N, Merajver SD, Janz NK, Copeland G, Roberts S. Recruiting families at risk for hereditary breast and ovarian cancer from a statewide cancer registry: a methodological study. Cancer Causes Control. 2017 Mar;28(3):191-201. doi: 10.1007/s10552-017-0858-2. Epub 2017 Feb 14.


Daly MB, Pilarski R, Berry M, Buys SS, Farmer M, Friedman S, Garber JE, Kauff ND, Khan S, Klein C, Kohlmann W, Kurian A, Litton JK, Madlensky L, Merajver SD, Offit K, Pal T, Reiser G, Shannon KM, Swisher E, Vinayak S, Voian NC, Weitzel JN, Wick MJ, Wiesner GL, Dwyer M, Darlow S.

​NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.

J Natl Compr Canc Netw. 2017 Jan;15(1):9-20.


2016

Allen SG, Chen YC, Madden JM, Fournier CL, Altemus MA, Hiziroglu AB, Cheng Y-H, Wu ZF, Bao L, Yates JA, Yoon E, Merajver SD. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling. Scientific Reports volume 6, Article number: 39190 (2016). DOI: 10.1038/srep39190


Cobain EF, Milliron KJ, Merajver SD. Updates on breast cancer genetics: Clinical implications of detecting syndromes of inherited increased susceptibility to breast cancer. Semin Oncol. 2016 Oct;43(5):528-535. doi: 10.1053/j.seminoncol.2016.10.001. Epub 2016 Oct 8. Review.


Jiagge E, Oppong JK, Aitpilla F, Gyan K, Kyei I, Osei-Bonsu E, Adjei E, Ohene-Yeboah M, Toy K, Jackson KE, Akpaloo M, Cheampong D, Antwi B, Agyeman FO, Alhassan Z, Fondjo LA, Owusu-Afriyie O, Brewer RN, Gyamfuah A, Salem B, Johnson T, Wicha M, Merajver SD, Kleer C, Pang J, Amankwaa-Frempong E, Stark A, Agantanga F, Newman L, Awuah B. Breast Cancer and African Ancestry: Lessons Learned at the 10-Year Anniversary of the Ghana-Michigan Research Partnership and International Breast Registry. J Glob Oncol. 2016 Jul 27;2(5):302-310. doi: 10.1200/JGO.2015.002881. eCollection 2016 Oct.


Jones T, Lockhart JS, Mendelsohn-Victor KE, Duquette D, Northouse LL, Duffy SA, Donley R, Merajver SD, Milliron KJ, Roberts JS, Katapodi MC.

​Use of Cancer Genetics Services in African-American Young Breast Cancer Survivors. Am J Prev Med. 2016 Oct;51(4):427-36. doi: 10.1016/j.amepre.2016.03.016. Epub 2016 Apr 23.


Allen SG, Soliman AS, Toy K, Omar OS, Youssef T, Karkouri M, Ayad E, Abdel-Aziz A, Hablas A, Tahri A, Oltean HN, Kleer CG, Merajver SD. Chronic Mastitis in Egypt and Morocco: Differentiating between Idiopathic Granulomatous Mastitis and IgG4-Related Disease. Breast J. 2016 Sep;22(5):501-9. doi: 10.1111/tbj.12628. Epub 2016 Jun 8.


Chen W, Allen SG, Reka AK, Qian W, Han S, Zhao J, Bao L, Keshamouni VG, Merajver SD, Fu J. Nanoroughened adhesion-based capture of circulating tumor cells with heterogeneous expression and metastatic characteristics. BMC Cancer. 2016 Aug 8;16:614. doi: 10.1186/s12885-016-2638-x.


Jiagge E, Jibril AS, Chitale D, Bensenhaver JM, Awuah B, Hoenerhoff M, Adjei E, Bekele M, Abebe E, Nathanson SD, Gyan K, Salem B, Oppong J, Aitpillah F, Kyei I, Bonsu EO, Proctor E, Merajver SD, Wicha M, Stark A, Newman LA. Comparative Analysis of Breast Cancer Phenotypes in African American, White American, and West Versus East African patients: Correlation Between African Ancestry and Triple-Negative Breast Cancer. Ann Surg Oncol. 2016 Jul 28.


Maslowsky J, Frost S, Hendrick CE, Trujillo Cruz FO, Merajver SD. Effects of postpartum mobile phone-based education on maternal and infant health in Ecuador.

Int J Gynaecol Obstet. 2016 Jul;134(1):93-8. doi: 10.1016/j.ijgo.2015.12.008. Epub 2016 Apr 8.


Wynn ML, Yates JA, Evans CR, Van Wassenhove LD, Wu ZF, Bridges S, Bao L, Fournier C, Ashrafzadeh S, Merrins MJ, Satin LS, Schnell S, Burant CF, Merajver SD.

RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. J Biol Chem. 2016 Jun 24;291(26):13715-29. doi: 10.1074/jbc.M115.703959. Epub 2016 Apr 25.


Iqbal J, Nussenzweig A, Lubinski J, Byrski T, Eisen A, Bordeleau L, Tung NM, Manoukian S, Phelan CM, Sun P, Narod SA; Hereditary Breast Cancer Research Group.

The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study. Br J Cancer. 2016 May 10;114(10):1160-4. doi: 10.1038/bjc.2016.58. Epub 2016 Mar 17.


Wynn M, Kidwell KM, Merajver SD. The Impact of Nathan Mantel's "The Detection of Disease Clustering and a Generalized Regression Approach".

Cancer Res. 2016 May 1;76(9):2495-6. doi: 10.1158/0008-5472.CAN-16-0883.


Kang Q, Henry NL, Paoletti C, Jiang H, Vats P, Chinnaiyan AM, Hayes DF, Merajver SD, Rae JM, Tewari M. Comparative analysis of circulating tumor DNA stability In K3EDTA, Streck, and CellSave blood collection tubes. Clin Biochem. 2016 Apr 27. pii: S0009-9120(16)30040-6. doi: 10.1016/j.clinbiochem.2016.03.012. [Epub ahead of print]


Jones T, Lockhart JS, Mendelsohn-Victor KE, Duquette D, Northouse LL, Duffy SA, Donley R, Merajver SD, Milliron KJ, Roberts JS, Katapodi MC.

Use of Cancer Genetics Services in African-American Young Breast Cancer Survivors. Am J Prev Med. 2016 Apr 22. pii: S0749-3797(16)30074-5. doi: 10.1016/j.amepre.2016.03.016.

Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J; Hereditary Breast Cancer Clinical Study Group. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertil Steril. 2016 Mar;105(3):781-5. doi: 10.1016/j.fertnstert.2015.11.034. Epub 2015 Dec 14.


Murthy P, Kidwell KM, Schott AF, Merajver SD, Griggs JJ, Smerage JD, Van Poznak CH, Wicha MS, Hayes DF, Henry NL. Clinical predictors of long-term survival in HER2-positive metastatic breast cancer. Breast Cancer Res Treat. 2016 Feb;155(3):589-95. doi: 10.1007/s10549-016-3705-3. Epub 2016 Feb 13.


Daly MB, Pilarski R, Axilbund JE, Berry M, Buys SS, Crawford B, Farmer M, Friedman S, Garber JE, Khan S, Klein C, Kohlmann W, Kurian A, Litton JK, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Rana H, Reiser G, Robson ME, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wick MJ, Wiesner GL, Dwyer M, Kumar R, Darlow S. Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015. J Natl Compr Canc Netw. 2016 Feb;14(2):153-62.


2015

Proctor E, Kidwell KM, Jiagge E, Bensenhaver J, Awuah B, Gyan K, Toy K, Oppong JK, Kyei I, Aitpillah F, Osei-Bonsu E, Adjei E, Ohene-Yeboah M, Brewer RN, Fondjo LA, Owusu-Afriyie O, Wicha M, Merajver S, Kleer C, Newman L. ​Characterizing Breast Cancer in a Population with Increased Prevalence of Triple-Negative Breast Cancer: Androgen Receptor and ALDH1 Expression in Ghanaian Women. Ann Surg Oncol. 2015 Nov;22(12):3831-5. doi: 10.1245/s10434-015-4455-x. Epub 2015 Mar 6.


Der EM, Gyasi RK, Tettey Y, Edusei L, Bayor MT, Jiagge E, Gyakobo M, Merajver SD, Newman LA. Triple-Negative Breast Cancer in Ghanaian Women: The Korle Bu Teaching Hospital Experience. Breast J. 2015 Nov-Dec;21(6):627-33. doi: 10.1111/tbj.12527.


Schlichting JA, Soliman AS, Schairer C, Harford JB, Hablas A, Ramadan M, Seifeldin I, Merajver SD. Breast cancer by age at diagnosis in the Gharbiah, Egypt, population-based registry compared to the United States Surveillance, Epidemiology, and End Results Program, 2004-2008. Biomed Res Int. 2015;2015:381574. doi: 10.1155/2015/381574. Epub 2015 Oct 1.


Song Q, Merajver SD, Li JZ. Cancer classification in the genomic era: five contemporary problems. Hum Genomics. 2015 Oct 19;9:27. doi: 10.1186/s40246-015-0049-8. Review.


Kotsopoulos J, Lubinski J, Gronwald J, Cybulski C, Demsky R, Neuhausen SL, Kim-Sing C, Tung N, Friedman S, Senter L, Weitzel J, Karlan B, Moller P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. ​Factors influencing ovulation and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. Int J Cancer. 2015 Sep 1;137(5):1136-46. doi: 10.1002/ijc.29386. Epub 2014 Dec 18.


Bevers TB, Ward JH, Arun BK, Colditz GA, Cowan KH, Daly MB, Garber JE, Gemignani ML, Gradishar WJ, Jordan JA, Korde LA, Kounalakis N, Krontiras H, Kumar S, Kurian A, Laronga C, Layman RM, Loftus LS, Mahoney MC, Merajver SD, Meszoely IM, Mortimer J, Newman L, Pritchard E, Pruthi S, Seewaldt V, Specht MC, Visvanathan K, Wallace A, Bergman MA, Kumar R. Breast Cancer Risk Reduction, Version 2.2015. J Natl Compr Canc Netw. 2015 Jul;13(7):880-915.


Kaushal N, Durmaz YY, Bao L, Merajver SD, ElSayed ME. "Smart" Nanoparticles Enhance the Cytoplasmic Delivery of Anti-RhoC Silencing RNA and Inhibit the Migration and Invasion of Aggressive Breast Cancer Cells. Mol Pharm. 2015 Jul 6;12(7):2406-17. doi: 10.1021/acs.molpharmaceut.5b00114. Epub 2015 May 28.

Chen YC, Allen SG, Ingram PN, Buckanovich R, Merajver SD, Yoon E. Single-cell Migration Chip for Chemotaxis-based Microfluidic Selection of Heterogeneous Cell Populations. Sci Rep. 2015 May 18;5:9980. doi: 10.1038/srep09980.


2014

Meernik C, Soliman AS, Ngoma T, Kahesa C, Mwaiselage J, Merajver SD. The changing pattern of ano-rectal cancer, squamous cell carcinoma of the eye, and Hodgkin's lymphoma as non-AIDS-defining cancers, by HIV status, in Tanzania over 11 years (2002-2012): a retrospective case-report study.​ Infect Agent Cancer. 2014 Dec 9;9:42. doi: 10.1186/1750-9378-9-42. eCollection 2014.


Wynn ML, Consul N, Merajver SD, Schnell S. Inferring the Effects of Honokiol on the Notch Signaling Pathway in SW480 Colon Cancer Cells. Cancer Inform. 2014 Oct 13;13(Suppl 5):1-12. doi: 10.4137/CIN.S14060. eCollection 2014.


Obrist M, Osei-Bonsu E, Awuah B, Watanabe-Galloway S, Merajver SD, Schmid K, Soliman AS. Factors related to incomplete treatment of breast cancer in Kumasi, Ghana. Breast. 2014 Dec;23(6):821-8. doi: 10.1016/j.breast.2014.08.014. Epub 2014 Oct 1.


Daly MB, Pilarski R, Axilbund JE, Buys SS, Crawford B, Friedman S, Garber JE, Horton C, Kaklamani V, Klein C, Kohlmann W, Kurian A, Litton J, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Pasche B, Reiser G, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wiesner GL, Dwyer MA, Kumar R. Genetic/Familial high-risk assessment: breast and ovarian, version 1.2014. J Natl Compr Canc Netw. 2014 Sep;12(9):1326-38.


Gronwald J, Robidoux A, Kim-Sing C, Tung N, Lynch HT, Foulkes WD, Manoukian S, Ainsworth P, Neuhausen SL, Demsky R, Eisen A, Singer CF, Saal H, Senter L, Eng C, Weitzel J, Moller P, Gilchrist DM, Olopade O, Ginsburg O, Sun P, Huzarski T, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2014 Jul;146(2):421-7. Epub 2014 Jun 21.


Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Merajver SD, Schwartz K. A comparison of criteria to identify inflammatory breast cancer cases from medical records and the Surveillance, Epidemiology and End Results data base, 2007-2009. Breast J. 2014 Mar-Apr;20(2):185-91. Epub 2013 Dec 26.


Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A, Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Res Treat. 2014 Feb;143(3):579-86. Epub 2014 Jan 24.


Scherber S, Soliman AS, Awuah B, Osei-Bonsu E, Adjei E, Abantanga F, Merajver SD. Characterizing breast cancer treatment pathways in Kumasi, Ghana from onset of symptoms to final outcome: Outlook towards cancer control. Breast Dis. 2014 Jan 1;34(4):139-49.

2013

Perng P, Perng W, Ngoma T, Kahesa C, Mwaiselage J, Merajver SD, Soliman AS. Promoters of and barriers to cervical cancer screening in a rural setting in Tanzania.

Int J Gynaecol Obstet. 2013 Dec;123(3):221-5. Epub 2013 Sep 4.


Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Chamberlain RM, Graff JJ, MerajverSD, Schwartz K. Characterizing inflammatory breast cancer among Arab Americans in the California, Detroit and New Jersey Surveillance, Epidemiology and End Results (SEER) registries (1988-2008). Springerplus. 2013 Dec;2(1):3. Epub 2013 Jan 7.


Semple J, Metcalfe KA, Lynch HT, Kim-Sing C, Senter L, Pal T, Ainsworth P, Lubinski J, Tung N, Eng C, Gilchrist D, Blum J, Neuhausen SL, Singer CF, Ghadirian P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers. Ann Surg Oncol. 2013 Nov;20(12):3817-22. Epub 2013 Jun 6.


Oltean HN, Soliman AS, Omar OS, Youssef TF, Karkouri M, Abdel-Aziz A, Hablas A, Blachley T, Tahri A, Merajver SD. Risk factors for chronic mastitis in morocco and egypt. Int J Inflam. 2013;2013:184921. Epub 2013 Nov 14.


Hirko KA, Soliman AS, Hablas A, Seifeldin IA, Ramadan M, Banerjee M, Harford JB, Chamberlain RM, Merajver SD. Trends in Breast Cancer Incidence Rates by Age and Stage at Diagnosis in Gharbiah, Egypt, over 10 Years (1999-2008). J Cancer Epidemiol. 2013;2013:916394. Epub 2013 Oct 24.


O'Brien KS, Soliman AS, Awuah B, Jiggae E, Osei-Bonsu E, Quayson S, Adjei E, Thaivalappil SS, Abantanga F, Merajver SD. Establishing effective registration systems in resource-limited settings: cancer registration in Kumasi, Ghana. J Registry Manag. 2013 Summer;40(2):70-7.


Katapodi MC, Northouse LL, Milliron KJ, Liu G, Merajver SD. Individual and family characteristics associated with BRCA1/2 genetic testing in high-risk families.

Psychooncology. 2013 Jun;22(6):1336-43. Epub 2012 Jul 24.


Finch A, Valentini A, Greenblatt E, Lynch HT, Ghadirian P, Armel S, Neuhausen SL, Kim-Sing C, Tung N, Karlan B, Foulkes WD, Sun P, Narod S; Hereditary Breast Cancer Study Group. Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation. Fertil Steril. 2013 May;99(6):1724-8. Epub 2013 Feb 13.


Akinyemiju TF, Soliman AS, Copeland G, Banerjee M, Schwartz K, Merajver SD. Trends in breast cancer stage and mortality in Michigan (1992-2009) by race, socioeconomic status, and area healthcare resources. PLoS One. 2013 Apr 29;8(4):e61879. Print 2013.


Schairer C, Soliman AS, Omar S, Khaled H, Eissa S, Ayed FB, Khalafallah S, Ayoub WB, Kantor ED,Merajver S, Swain SM, Gail M, Brown LM. Assessment of diagnosis of inflammatory breast cancer cases at two cancer centers in Egypt and Tunisia. Cancer Med. 2013 Apr;2(2):178-84. Epub 2013 Jan 24.


Schneider BJ, Lee JS, Hayman JA, Chang AC, Orringer MB, Pickens A, Pan CC, Merajver SD, Urba SG. Pre-operative chemoradiation followed by post-operative adjuvant therapy with tetrathiomolybdate, a novel copper chelator, for patients with resectable esophageal cancer. Invest New Drugs. 2013 Apr;31(2):435-42. Epub 2012 Jul 31.


Katapodi MC, Northouse LL, Schafenacker AM, Duquette D, Duffy SA, Ronis DL, Anderson B, Janz NK, McLosky J, Milliron KJ, Merajver SD, Duong LM, Copeland G.

Using a state cancer registry to recruit young breast cancer survivors and high-risk relatives: protocol of a randomized trial testing the efficacy of a targeted versus a tailored intervention to increase breast cancer screening. BMC Cancer. 2013 Mar 1;13:97.


Balkrishnan R, Chang J, Patel I, Yang F, Merajver SD. Global comparative healthcare effectiveness research: evaluating sustainable programmes in low & middle resource settings. Indian J Med Res. 2013 Mar;137(3):494-501. Review.


Chen W, Weng S, Zhang F, Allen S, Li X, Bao L, Lam RH, Macoska JA, Merajver SD, Fu J. Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies. ACS Nano. 2013 Jan 22;7(1):566-75. Epub 2012 Dec 5.


Akinyemiju TF, Soliman AS, Johnson NJ, Altekruse SF, Welch K, Banerjee M, Schwartz K, Merajver SD. Individual and neighborhood socioeconomic status and healthcare resources in relation to black-white breast cancer survival disparities. J Cancer Epidemiol. 2013;2013:490472. Epub 2013 Feb 20.

2012

Wynn ML, Consul N, Merajver SD, Schnell S. Logic-based models in systems biology: a predictive and parameter-free network analysis method.

Integr Biol (Camb). 2012 Nov 4.


Soliman AS, Kleer CG, Mrad K, Karkouri M, Omar S, Khaled HM, Benider AL, Ayed FB, Eissa SS, Eissa MS, McSpadden EJ, Lo AC, Toy K, Kantor ED, Xiao Q, Hampton C, Merajver SD. Inflammatory breast cancer in North Africa: Comparison of clinical and molecular epidemiologic characteristics of patients from Egypt, Tunisia, and Morocco. Breast Dis. 2012 Sep 21.


Rosenthal DT, Zhang J, Bao L, Zhu L, Wu Z, Toy K, Kleer CG, Merajver SD. RhoC Impacts the Metastatic Potential and Abundance of Breast Cancer Stem Cells.

PLoS One. 2012;7(7):e40979. Epub 2012 Jul 23.


Sepulchre JA, Merajver SD, Ventura AC. Retroactive signaling in short signaling pathways. PLoS One. 2012;7(7):e40806. Epub 2012 Jul 26.


Schneider BJ, Lee JS, Hayman JA, Chang AC, Orringer MB, Pickens A, Pan CC, Merajver SD, Urba SG. Pre-operative chemoradiation followed by post-operative adjuvant therapy with tetrathiomolybdate, a novel copper chelator, for patients with resectable esophageal cancer. Invest New Drugs. 2012 Jul 31.


Katapodi MC, Northouse LL, Milliron KJ, Liu G, Merajver SD. Individual and family characteristics associated with BRCA1/2 genetic testing in high-risk families.

Psychooncology. 2012 Jul 24. doi: 10.1002/pon.3139.


Schlichting JA, Soliman AS, Schairer C, Schottenfeld D, Merajver SD. Inflammatory and non-inflammatory breast cancer survival by socioeconomic position in the Surveillance, Epidemiology, and End Results database, 1990-2008. Breast Cancer Res Treat. 2012 Aug;134(3):1257-68. Epub 2012 Jun 26.


O'Brien KS, Soliman AS, Annan K, Lartey RN, Awuah B, Merajver SD. Traditional herbalists and cancer management in kumasi, ghana. J Cancer Educ. 2012 Jun;27(3):573-9.


Rosenthal DT, Merajver SD. Rethinking the war on cancer: multidisciplinary collaborations between biologists and physical scientists.

Future Oncol. 2012 Apr;8(4):339-41.


Wynn ML, Merajver SD, Schnell S. Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer.

Adv Exp Med Biol. 2012;736:179-89.


Uddin N, Fateem E, Hablas A, Seifeldin IA, Brown E, Merajver SD, Soliman AS. Public and professional educational needs for downstaging breast cancer in egypt.

J Cancer Educ. 2012 Mar;27(1):149-55.


Uddin N, Fateem E, Hablas A, Seifeldin IA, Brown E, Merajver SD, Soliman AS. Erratum to: Public and Professional Educational Needs for Downstaging Breast Cancer in Egypt. J Cancer Educ. 2012 Jan 13.


Wynn ML, Merajver SD, Schnell S. Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer.

Adv Exp Med Biol. 2012;736:179-89.


Schlichting JA, Soliman AS, Schairer C, Banerjee M, Rozek LS, Schottenfeld D, Harford JB, Merajver SD. Association of inflammatory and noninflammatory breast cancer with socioeconomic characteristics in the Surveillance, Epidemiology, and End Results database, 2000-2007. Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):155-65. Epub 2011 Oct 25.

2011

Rosenthal DT, Iyer H, Escudero S, Bao L, Wu Z, Ventura AC, Kleer CG, Arruda EM, Garikipati K, Merajver SD.

p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior.

Cancer Res. 2011 Oct 15;71(20):6338-49. Epub 2011 Aug 23.


Merajver SD, Balkrishnan R. Making the case for integrated assessments of the biological, social, and system determinants of treatment for breast cancer to understand and improve outcomes in patients everywhere. Curr Med Res Opin. 2011 Oct 14.


Jiang P, Ventura AC, Sontag ED, Merajver SD, Ninfa AJ, Del Vecchio D. Load-induced modulation of signal transduction networks.

Sci Signal. 2011 Oct 11;4(194):ra67. doi: 10.1126/scisignal.2002152.


Wynn ML, Ventura AC, Sepulchre JA, García HJ, Merajver SD. Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity.

BMC Syst Biol. 2011 Oct 4;5:156.


Gilbert SF, Soliman AS, Iniesta M, Eissa M, Hablas A, Seifeldin IA, Strahley A, Banerjee M, Merajver SD. Androgen receptor polyglutamine tract length in Egyptian male breast cancer patients. Breast Cancer Res Treat. 2011 Sep;129(2):575-81. doi: 10.1007/s10549-011-1510-6. Epub 2011 Apr 20.


Spencer B, Banerjee M, Omar S, Khaled H, Anwar N, Zaghloul MS, Eissa S, Kleer CG, Dey S, Merajver SD, Soliman AS. Survival of inflammatory breast cancer patients compared to non-inflammatory breast cancer patients in Egypt. Breast J. 2011 Sep-Oct;17(5):545-7. doi: 10.1111/j.1524-4741.2011.01146.x. Epub 2011 Aug 9.


Katapodi MC, Northouse L, Pierce P, Milliron KJ, Liu G, Merajver SD. Differences between women who pursued genetic testing for hereditary breast and ovarian cancer and their at-risk relatives who did not. Oncol Nurs Forum. 2011 Sep;38(5):572-81.


Alford SH, Toy K, Merajver SD, Kleer CG. Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression.

Breast Cancer Res Treat. 2011 May 26.


Ossareh HR, Ventura AC, Merajver SD, Del Vecchio D. Long signaling cascades tend to attenuate retroactivity. Biophys J. 2011 Apr 6;100(7):1617-26.


Gonzalez ME, DuPrie ML, Krueger H, Merajver SD, Ventura AC, Toy KA, Kleer CG. Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer. Cancer Res. 2011 Mar 15;71(6):2360-70.


Dawood S, Merajver SD, Viens P, Vermeulen PB, Swain SM, Buchholz TA, Dirix LY, Levine PH, Lucci A, Krishnamurthy S, Robertson FM, Woodward WA, Yang WT, Ueno NT, Cristofanilli M. International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment. Ann Oncol. 2011 Mar;22(3):515-23. Epub 2010 Jul 5.


Bosch-Barrera J, Merajver SD, Menéndez JA, Van Poznak C. Direct antitumour activity of zoledronic acid: preclinical and clinical data. Clin Transl Oncol. 2011 Mar;13(3):148-55. Review.


Gilbert SF, Soliman AS, Karkouri M, Quinlan-Davidson M, Strahley A, Eissa M, Dey S, Hablas A, Seifeldin IA, Ramadan M, Benjaafar N, Toy K, Merajver SD.

Clinical profile, BRCA2 expression, and the androgen receptor CAG repeat region in Egyptian and Moroccan male breast cancer patients. Breast Dis. 2011 Jan 1;33(1):17-26.

2010

Varedi K SM, Ventura AC, Merajver SD, Lin XN. Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation. PLoS One. 2010 Dec 13;5(12):e14029.


Iniesta MD, Gorin MA, Chien LC, Thomas SM, Milliron KJ, Douglas JA, Merajver SD. Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America. Cancer Genet Cytogenet. 2010 Oct 15;202(2):136-40.


Dey S, Soliman AS, Hablas A, Seifeldein IA, Ismail K, Ramadan M, El-Hamzawy H, Wilson ML, Banerjee M, Boffetta P, Harford J, Merajver SD. Urban-rural differences in breast cancer incidence in Egypt (1999-2006).Breast. 2010 Oct;19(5):417-23. Epub 2010 May 8.


Bevers TB, Armstrong DK, Arun B, Carlson RW, Cowan KH, Daly MB, Fleming I, Garber JE, Gemignani M, Gradishar WJ, Krontiras H, Kulkarni S, Laronga C, Loftus L, Macdonald DJ, Mahoney MC, Merajver SD, Meszoely I, Newman L, Pritchard E, Seewaldt V, Sellin RV, Shapiro CL, Ward JH.

Breast cancer risk reduction.J Natl Compr Canc Netw. 2010 Oct;8(10):1112-46.


Kumar P, Yadav A, Patel SN, Islam M, Pan Q, Merajver SD, Teknos TN. Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol Cancer. 2010 Aug 3;9:206.


Pierce LJ, Phillips KA, Griffith KA, Buys S, Gaffney DK, Moran MS, Haffty BG, Ben-David M, Kaufman B, Garber JE, Merajver SD, Balmaña J, Meirovitz A, Domchek SM. Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy. Breast Cancer Res Treat. 2010 Jun;121(2):389-98. Epub 2010 Apr 22.


Wu M, Wu ZF, Rosenthal DT, Rhee EM, Merajver SD. Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers. Cancer. 2010 Jun 1;116(11 Suppl):2768-82.


Ventura AC, Jiang P, Van Wassenhove L, Del Vecchio D, Merajver SD, Ninfa AJ. Signaling properties of a covalent modification cycle are altered by a downstream target. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10032-7. Epub 2010 May 17.


Dey S, Hablas A, Seifeldin IA, Ismail K, Ramadan M, El-Hamzawy H, Wilson ML, Banerjee M, Boffetta P, Harford J, Merajver SD, Soliman AS. Urban-rural differences of gynaecological malignancies in Egypt (1999-2002). BJOG. 2010 Feb;117(3):348-55. Epub 2009 Dec 16.


Dey S, Soliman AS, Hablas A, Seifeldin IA, Ismail K, Ramadan M, El-Hamzawy H, Wilson ML, Banerjee M, Boffetta P, Harford J, Merajver SD. Urban-rural differences in breast cancer incidence by hormone receptor status across 6 years in Egypt. Breast Cancer Res Treat. 2010 Feb;120(1):149-60. Epub 2009 Jun 23.


Burson AM, Soliman AS, Ngoma TA, Mwaiselage J, Ogweyo P, Eissa MS, Dey S, Merajver SD. Clinical and epidemiologic profile of breast cancer in Tanzania. Breast Dis. 2010;31(1):33-41.


Iniesta MD, Chien J, Wicha M, Merajver SD. One-hit effects and cancer.Cancer Prev Res (Phila). 2010 Jan;3(1):12-5. Review.


Rosenthal DT, Iyer H, Escudero S, Ventura AC, Arruda EM, Garikipati K, Merajver SD. From in vitro to in silico and back again: using biological and mathematical synergy to decipher breast cancer cell motility. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:3261-4

2009

Pan Q, Rosenthal DT, Bao L, Kleer CG, Merajver SD. Antiangiogenic tetrathiomolybdate protects against Her2/neu-induced breast carcinoma by hypoplastic remodeling of the mammary gland.Clin Cancer Res. 2009 Dec 1;15(23):7441-6. Epub 2009 Nov 24.


Iniesta MD, Mooney CJ, Merajver SD. Inflammatory breast cancer: what are the treatment options? Expert Opin Pharmacother. 2009 Dec;10(18):2987-97. Review.


Chang CW, Wu M, Merajver SD, Mycek MA. Physiological fluorescence lifetime imaging microscopy improves Förster resonance energy transfer detection in living cells. J Biomed Opt. 2009 Nov-Dec;14(6):060502.


Islam M, Lin G, Brenner JC, Pan Q, Merajver SD, Hou Y, Kumar P, Teknos TN. RhoC expression and head and neck cancer metastasis. Mol Cancer Res. 2009 Nov;7(11):1771-80. Epub 2009 Oct 27.


Li X, Gonzalez ME, Toy K, Filzen T, Merajver SD, Kleer CG. Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia.Am J Pathol. 2009 Sep;175(3):1246-54. Epub 2009 Aug 6.


Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD. Pomegranate fruit extract impairs invasion and motility in human breast cancer.Integr Cancer Ther. 2009 Sep;8(3):242-53.


Bao L, Gorin MA, Zhang M, Ventura AC, Pomerantz WC, Merajver SD, Teknos TN, Mapp AK, Pan Q. Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer.Cancer Res. 2009 Jul 15;69(14):5829-34. Epub 2009 Jun 30.


Soliman AS, Banerjee M, Lo AC, Ismail K, Hablas A, Seifeldin IA, Ramadan M, Omar HG, Fokuda A, Harford JB, Merajver SD.

High proportion of inflammatory breast cancer in the Population-based Cancer Registry of Gharbiah, Egypt.

Breast J. 2009 Jul-Aug;15(4):432-4.


Dey S, Soliman AS, Merajver SD.

Xenoestrogens may be the cause of high and increasing rates of hormone receptor positive breast cancer in the world.

Med Hypotheses. 2009 Jun;72(6):652-6. Epub 2009 Jan 19.


Gartner EM, Griffith KA, Pan Q, Brewer GJ, Henja GF, Merajver SD, Zalupski MM.

A pilot trial of the anti-angiogenic copper lowering agent tetrathiomolybdate in combination with irinotecan, 5-flurouracil, and leucovorin for metastatic colorectal cancer.

Invest New Drugs. 2009 Apr;27(2):159-65. Epub 2008 Aug 20.


Hensley Alford S, Schwartz K, Soliman A, Johnson CC, Gruber SB, Merajver SD.

Breast cancer characteristics at diagnosis and survival among Arab-American women compared to European- and African-American women.

Breast Cancer Res Treat. 2009 Mar;114(2):339-46. Epub 2008 Apr 15.


Gonzalez ME, Li X, Toy K, DuPrie M, Ventura AC, Banerjee M, Ljungman M, Merajver SD, Kleer CG.

Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1.

Oncogene. 2009 Feb 12;28(6):843-53. Epub 2008 Dec 15.


Lo AC, Georgopoulos A, Kleer CG, Banerjee M, Omar S, Khaled H, Eissa S, Hablas A, Omar HG, Douglas JA, Merajver SD, Soliman AS.

Analysis of RhoC expression and lymphovascular emboli in inflammatory vs non-inflammatory breast cancers in Egyptian patients.

Breast. 2009 Feb;18(1):55-9. Epub 2009 Jan 20.


Ventura AC, Jackson TL, Merajver SD.

On the role of cell signaling models in cancer research.

Cancer Res. 2009 Jan 15;69(2):400-2. Review.


Wasielewski M, Hanifi-Moghaddam P, Hollestelle A, Merajver SD, van den Ouweland A, Klijn JG, Ethier SP, Schutte M.

Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.

Breast Cancer Res Treat. 2009 Jan;113(2):285-91. Epub 2008 Feb 24.

2008

Houchens NW, Merajver SD.

Molecular determinants of the inflammatory breast cancer phenotype.

Oncology (Williston Park). 2008 Dec;22(14):1556-61; discussion 1561, 1565-8, 1576.


Lo AC, Kleer CG, Banerjee M, Omar S, Khaled H, Eissa S, Hablas A, Douglas JA, Alford SH, Merajver SD, Soliman AS.

Molecular epidemiologic features of inflammatory breast cancer: a comparison between Egyptian and US patients.

Breast Cancer Res Treat. 2008 Nov;112(1):141-7. Epub 2007 Dec 4.


Ho TT, Merajver SD, Lapière CM, Nusgens BV, Deroanne CF.

RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.

J Biol Chem. 2008 Aug 1;283(31):21588-98. Epub 2008 Jun 4.


Iniesta MD, Merajver SD.

CHEK2 screening: do not think so globally yet.

J Clin Oncol. 2008 Jun 20;26(18):3092; author reply 3093-4.


Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, Kleer CG.

Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

Am J Pathol. 2008 Apr;172(4):893-904. Epub 2008 Mar 5.


Ventura AC, Sepulchre JA, Merajver SD.

A hidden feedback in signaling cascades is revealed.

PLoS Comput Biol. 2008 Mar 21;4(3):e1000041.


Liu S, Ginestier C, Charafe-Jauffret E, Foco H, Kleer CG, Merajver SD, Dontu G, Wicha MS.

BRCA1 regulates human mammary stem/progenitor cell fate.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1680-5. Epub 2008 Jan 29.


Ventura AC, Merajver SD.

Genetic determinants of aggressive breast cancer.

Annu Rev Med. 2008;59:199-212. Review.

2007

Zhong W, Wu M, Chang CW, Merrick KA, Merajver SD, Mycek MA.

Picosecond-resolution fluorescence lifetime imaging microscopy: a useful tool for sensing molecular interactions in vivo via FRET.

Opt Express. 2007 Dec 24;15(26):18220-35.


Bevers TB, Armstrong DK, Arun B, Carlson RW, Cowan KH, Daly MB, Fleming I, Garber JE, Gemignani M, Gradishar WJ, Krontiras H, Kulkarni S, Laronga C, Lawton T, Loftus L, Macdonald DJ, Mahoney MC, Merajver SD, Seewaldt V, Sellin RV, Shapiro CL, Singletary E, Ward JH; National Comprehensive Cancer Network (NCCN).

Breast cancer risk reduction.

J Natl Compr Canc Netw. 2007 Sep;5(8):676-701.


Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí­ JA, Merajver SD, Neubig RR.

CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.

Mol Cancer Ther. 2007 Aug;6(8):2249-60.


Hassouneh B, Islam M, Nagel T, Pan Q, Merajver SD, Teknos TN.

Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer.

Mol Cancer Ther. 2007 Mar;6(3):1039-45.


Wu M, Wu ZF, Merajver SD.

Rho proteins and cell-matrix interactions in cancer.

Cells Tissues Organs. 2007;185(1-3):100-3. Review.


Kleer CG, Zhang Y, Merajver SD.

CCN6 (WISP3) as a new regulator of the epithelial phenotype in breast cancer.

Cells Tissues Organs. 2007;185(1-3):95-9. Review.


Khan GN, Merajver SD.

Modulation of angiogenesis for cancer prevention: strategies based on antioxidants and copper deficiency.

Curr Pharm Des. 2007;13(35):3584-90. Review.

2006

Pan Q, Bao LW, Teknos TN, Merajver SD.

Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.

Cancer Res. 2006 Oct 1;66(19):9379-84.


Shah NM, Soliman AS, Benerjee M, Merajver SD, Ismail K, Seifeldin I, Hablas A, Zarzour A, Abdel-Aziz A, Ben Ayed F, Chamberlain RM.

Knowledge gained after a brief CME module on breast cancer diagnosis.

J Cancer Educ. 2006 Fall;21(3):169-74.


Kleer CG, Teknos TN, Islam M, Marcus B, Lee JS, Pan Q, Merajver SD.

RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck.

Clin Cancer Res. 2006 Aug 1;12(15):4485-90.


Pierce LJ, Levin AM, Rebbeck TR, Ben-David MA, Friedman E, Solin LJ, Harris EE, Gaffney DK, Haffty BG, Dawson LA, Narod SA, Olivotto IA, Eisen A, Whelan TJ, Olopade OI, Isaacs C, Merajver SD, Wong JS, Garber JE, Weber BL.

Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.

J Clin Oncol. 2006 Jun 1;24(16):2437-43. Epub 2006 Apr 24.


Ding L, Erdmann C, Chinnaiyan AM, Merajver SD, Kleer CG.

Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues.

Cancer Res. 2006 Apr 15;66(8):4095-9.


Khan MK, Mamou F, Schipper MJ, May KS, Kwitny A, Warnat A, Bolton B, Nair BM, Kariapper MS, Miller M, Brewer G, Normolle D, Merajver SD, Teknos TN.

Combination tetrathiomolybdate and radiation therapy in a mouse model of head and neck squamous cell carcinoma.

Arch Otolaryngol Head Neck Surg. 2006 Mar;132(3):333-8.


Van den Eynden GG, Van Laere SJ, Van der Auwera I, Merajver SD, Van Marck EA, van Dam P, Vermeulen PB, Dirix LY, van Golen KL.

Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer.

Breast Cancer Res Treat. 2006 Feb;95(3):219-28. Epub 2005 Oct 22.


Elstrodt F, Hollestelle A, Nagel JH, Gorin M, Wasielewski M, van den Ouweland A, Merajver SD, Ethier SP, Schutte M.

BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants.

Cancer Res. 2006 Jan 1;66(1):41-5.

2005

Goodman VL, Brewer GJ, Merajver SD.

Control of copper status for cancer therapy.

Curr Cancer Drug Targets. 2005 Nov;5(7):543-9. Review.


Zeidler M, Varambally S, Cao Q, Chinnaiyan AM, Ferguson DO, Merajver SD, Kleer CG.

The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells.

Neoplasia. 2005 Nov;7(11):1011-9.


Merajver SD, Usmani SZ.

Multifaceted role of Rho proteins in angiogenesis.

J Mammary Gland Biol Neoplasia. 2005 Oct;10(4):291-8. Review.


Pan Q, Bao LW, Kleer CG, Sabel MS, Griffith KA, Teknos TN, Merajver SD.

Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy.

Cancer Res. 2005 Sep 15;65(18):8366-71.


Kleer CG, Griffith KA, Sabel MS, Gallagher G, van Golen KL, Wu ZF, Merajver SD.

RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast.

Breast Cancer Res Treat. 2005 Sep;93(2):101-10.


Lin M, DiVito MM, Merajver SD, Boyanapalli M, van Golen KL.

Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1.

Mol Cancer. 2005 Jun 21;4(1):21.


Wang C, Gonzalez R, Milliron KJ, Strecher VJ, Merajver SD.

Genetic counseling for BRCA1/2: a randomized controlled trial of two strategies to facilitate the education and counseling process.

Am J Med Genet A. 2005 Apr 1;134A(1):66-73.


Teknos TN, Islam M, Arenberg DA, Pan Q, Carskadon SL, Abarbanell AM, Marcus B, Paul S, Vandenberg CD, Carron M, Nor JE, Merajver SD.

The effect of tetrathiomolybdate on cytokine expression, angiogenesis, and tumor growth in squamous cell carcinoma of the head and neck.

Arch Otolaryngol Head Neck Surg. 2005 Mar;131(3):204-11.


Zhang Y, Pan Q, Zhong H, Merajver SD, Kleer CG.

Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.

Breast Cancer Res. 2005;7(6):R1080-9. Epub 2005 Nov 8.


Wu M, Merajver SD.

Molecular biology of inflammatory breast cancer: applications to diagnosis, prognosis, and therapy.

Breast Dis. 2005-2006;22:25-34. Review.

2004

Marcus B, Arenberg D, Lee J, Kleer C, Chepeha DB, Schmalbach CE, Islam M, Paul S, Pan Q, Hanash S, Kuick R, Merajver SD, Teknos TN.

Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma.

Cancer. 2004 Dec 15;101(12):2779-87.


Goodman VL, Brewer GJ, Merajver SD.

Copper deficiency as an anti-cancer strategy.

Endocr Relat Cancer. 2004 Jun;11(2):255-63. Review.


Wang C, Gonzalez R, Merajver SD.

Assessment of genetic testing and related counseling services: current research and future directions.

Soc Sci Med. 2004 Apr;58(7):1427-42.


Wu M, Wu ZF, Kumar-Sinha C, Chinnaiyan A, Merajver SD.

RhoC induces differential expression of genes involved in invasion and metastasis in MCF10A breast cells.

Breast Cancer Res Treat. 2004 Mar;84(1):3-12.


Kleer CG, Zhang Y, Pan Q, Merajver SD.

WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancer.

Neoplasia. 2004 Mar-Apr;6(2):179-85.


Kleer CG, Zhang Y, Pan Q, Gallagher G, Wu M, Wu ZF, Merajver SD.

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer.

Breast Cancer Res. 2004;6(2):R110-5.


Kleer CG, Zhang Y, Pan Q, Gallagher G, Wu M, Wu ZF, Merajver SD.

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer.

Breast Cancer Res. 2004;6(1):R110-5.

2003

Collisson EA, Kleer C, Wu M, De A, Gambhir SS, Merajver SD, Kolodney MS.

Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells.

Mol Cancer Ther. 2003 Oct;2(10):941-8.


Pan Q, Bao LW, Merajver SD.

Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade.

Mol Cancer Res. 2003 Aug;1(10):701-6.


Cox C, Merajver SD, Yoo S, Dick RD, Brewer GJ, Lee JS, Teknos TN.

Inhibition of the growth of squamous cell carcinoma by tetrathiomolybdate-induced copper suppression in a murine model.

Arch Otolaryngol Head Neck Surg. 2003 Jul;129(7):781-5.


Pan Q, Bao LW, Kleer CG, Brewer GJ, Merajver SD.

Antiangiogenic tetrathiomolybdate enhances the efficacy of doxorubicin against breast carcinoma.

Mol Cancer Ther. 2003 Jul;2(7):617-22.


Redman BG, Esper P, Pan Q, Dunn RL, Hussain HK, Chenevert T, Brewer GJ, Merajver SD.

Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer.

Clin Cancer Res. 2003 May;9(5):1666-72.


Merajver SD, Milliron K.

Breast cancer risk assessment: a guide for clinicians using the NCCN Breast Cancer Risk Reduction Guidelines.

J Natl Compr Canc Netw. 2003 Apr;1(2):297-301.

2002

Brewer GJ, Merajver SD.

Cancer therapy with tetrathiomolybdate: antiangiogenesis by lowering body copper--a review.

Integr Cancer Ther. 2002 Dec;1(4):327-37. Review.


Pan Q, Kleer CG, van Golen KL, Irani J, Bottema KM, Bias C, De Carvalho M, Mesri EA, Robins DM, Dick RD, Brewer GJ, Merajver SD.

Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.

Cancer Res. 2002 Sep 1;62(17):4854-9.


van Golen KL, Bao L, Brewer GJ, Pienta KJ, Kamradt JM, Livant DL, Merajver SD.

Suppression of tumor recurrence and metastasis by a combination of the PHSCN sequence and the antiangiogenic compound tetrathiomolybdate in prostate carcinoma.

Neoplasia. 2002 Sep-Oct;4(5):373-9.


Kleer CG, Tseng MD, Gutsch DE, Rochford RA, Wu Z, Joynt LK, Helvie MA, Chang T, Van Golen KL, Merajver SD.

Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts.

Mod Pathol. 2002 Jul;15(7):759-64.


Munshi HG, Merajver SD, Valdez R, Baker LH, Cooney KA.

Metastatic dedifferentiated chordoma with elevated beta-hCG: a case report.

Am J Clin Oncol. 2002 Jun;25(3):274-6.


van Golen KL, Bao L, DiVito MM, Wu Z, Prendergast GC, Merajver SD.

Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor.

Mol Cancer Ther. 2002 Jun;1(8):575-83.


Kleer CG, Zhang Y, Pan Q, van Golen KL, Wu ZF, Livant D, Merajver SD.

WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.

Oncogene. 2002 May 9;21(20):3172-80.


Khan MK, Miller MW, Taylor J, Gill NK, Dick RD, Van Golen K, Brewer GJ, Merajver SD.

Radiotherapy and antiangiogenic TM in lung cancer.

Neoplasia. 2002 Mar-Apr;4(2):164-70.


Kleer CG, van Golen KL, Zhang Y, Wu ZF, Rubin MA, Merajver SD.

Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability.

Am J Pathol. 2002 Feb;160(2):579-84.


Peterson EA, Milliron KJ, Lewis KE, Goold SD, Merajver SD.

Health insurance and discrimination concerns and BRCA1/2 testing in a clinic population.

Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):79-87.


van Golen KL, Bao LW, Pan Q, Miller FR, Wu ZF, Merajver SD.

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer.

Clin Exp Metastasis. 2002;19(4):301-11.

2001

Trask PC, Paterson AG, Wang C, Hayasaka S, Milliron KJ, Blumberg LR, Gonzalez R, Murray S, Merajver SD.

Cancer-specific worry interference in women attending a breast and ovarian cancer risk evaluation program: impact on emotional distress and health functioning.

Psychooncology. 2001 Sep-Oct;10(5):349-60.


Kleer CG, van Golen KL, Braun T, Merajver SD.

Persistent E-cadherin expression in inflammatory breast cancer.

Mod Pathol. 2001 May;14(5):458-64.


Cox C, Teknos TN, Barrios M, Brewer GJ, Dick RD, Merajver SD.

The role of copper suppression as an antiangiogenic strategy in head and neck squamous cell carcinoma.

Laryngoscope. 2001 Apr;111(4 Pt 1):696-701.

2000

van Golen KL, Wu ZF, Qiao XT, Bao LW, Merajver SD.

RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype.

Cancer Res. 2000 Oct 15;60(20):5832-8.


van Golen KL, Wu ZF, Qiao XT, Bao L, Merajver SD.

RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells.

Neoplasia. 2000 Sep-Oct;2(5):418-25.


Kleer CG, van Golen KL, Merajver SD.

Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants.

Breast Cancer Res. 2000;2(6):423-9. Epub 2000 Jul 11. Review.


Brewer GJ, Dick RD, Grover DK, LeClaire V, Tseng M, Wicha M, Pienta K, Redman BG, Jahan T, Sondak VK, Strawderman M, LeCarpentier G, Merajver SD.

Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study.

Clin Cancer Res. 2000 Jan;6(1):1-10.

1999

van Golen KL, Davies S, Wu ZF, Wang Y, Bucana CD, Root H, Chandrasekharappa S, Strawderman M, Ethier SP, Merajver SD.

A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.

Clin Cancer Res. 1999 Sep;5(9):2511-9.


van Golen K, Milliron K, Davies S, Merajver SD.

BRCA-associated cancer risk: molecular biology and clinical practice.

J Lab Clin Med. 1999 Jul;134(1):11-8. Review.

1997

Merajver SD, Weber BL, Cody R, Zhang D, Strawderman M, Calzone KA, LeClaire V, Levin A, Irani J, Halvie M, August D, Wicha M, Lichter A, Pierce LJ.

Breast conservation and prolonged chemotherapy for locally advanced breast cancer: the University of Michigan experience.

J Clin Oncol. 1997 Aug;15(8):2873-81.


Helvie MA, Roubidoux MA, Weber BL, Merajver SD.

Mammography of breast carcinoma in women who have mutations of the breast cancer gene BRCA1: initial experience.

AJR Am J Roentgenol. 1997 Jun;168(6):1599-602.

1996

Abel KJ, Brody LC, Valdes JM, Erdos MR, McKinley DR, Castilla LH, Merajver SD, Couch FJ, Friedman LS, Ostermeyer EA, Lynch ED, King MC, Welcsh PL, Osborne-Lawrence S, Spillman M, Bowcock AM, Collins FS, Weber BL.

Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.

Genomics. 1996 Oct 15;37(2):161-71.


Caduff RF, Johnston CM, Svoboda-Newman SM, Poy EL, Merajver SD, Frank TS.

Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.

Am J Pathol. 1996 May;148(5):1671-8.


Simon JS, Deshmukh G, Couch FJ, Merajver SD, Weber BL, Van Vooren P, Tissil F, Szpirer J, Szpirer C, Alper SL, Jacob HJ, Brosius FC 3rd.

Chromosomal mapping of the rat Slc4a family of anion exchanger genes, Ae1, Ae2, and Ae3.

Mamm Genome. 1996 May;7(5):380-2.


Cooney KA, Wetzel JC, Merajver SD, Macoska JA, Singleton TP, Wojno KJ.

Distinct regions of allelic loss on 13q in prostate cancer.

Cancer Res. 1996 Mar 1;56(5):1142-5.


Merajver SD, Petty EM.

Risk assessment and presymptomatic molecular diagnosis in hereditary breast cancer.

Clin Lab Med. 1996 Mar;16(1):139-67.


Helvie MA, Joynt LK, Cody RL, Pierce LJ, Adler DD, Merajver SD.

Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.

Radiology. 1996 Feb;198(2):327-32.

1995

Merajver SD, Frank TS, Xu J, Pham TM, Calzone KA, Bennett-Baker P, Chamberlain J, Boyd J, Garber JE, Collins FS, et al.

Germline BRCA1 mutations and loss of the wild-type allele in tumors from families with early onset breast and ovarian cancer.

Clin Cancer Res. 1995 May;1(5):539-44.


Merajver SD, Pham TM, Caduff RF, Chen M, Poy EL, Cooney KA, Weber BL, Collins FS, Johnston C, Frank TS.

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.

Nat Genet. 1995 Apr;9(4):439-43.


Hoskins KF, Stopfer JE, Calzone KA, Merajver SD, Rebbeck TR, Garber JE, Weber BL.

Assessment and counseling for women with a family history of breast cancer. A guide for clinicians.

JAMA. 1995 Feb 15;273(7):577-85.


Couch FJ, Garber J, Kiousis S, Calzone K, Hauser ER, Merajver SD, Frank TS, Boehnke M, Chamberlain JS, Collins FS, et al.

Genetic analysis of eight breast-ovarian cancer families with suspected BRCA1 mutations.

J Natl Cancer Inst Monogr. 1995;(17):9-14.

1994

Weber BL, Abel KJ, Brody LC, Flejter WL, Chandrasekharappa SC, Couch FJ, Merajver SD, Collins FS.

Familial breast cancer. Approaching the isolation of a susceptibility gene.

Cancer. 1994 Aug 1;74(3 Suppl):1013-20. Review.


Weber BL, Abel KJ, Couch FJ, Merajver SD, Chandrasekharappa SC, Castilla L, McKinley D, Ho PP, Calzone K, Frank TS, et al.

Progress toward isolation of a breast cancer susceptibility gene, BRCA1.

Cold Spring Harb Symp Quant Biol. 1994;59:531-6.

1987

Kikuchi GE, Baker SA, Merajver SD, Coligan JE, Levine M, Glorioso JC, Nairn R.

Purification and structural characterization of herpes simplex virus glycoprotein C.

Biochemistry. 1987 Jan 27;26(2):424-31.

1981

Merajver SD, Sheridan JP, Siguel EN.

Theory of the conformational order of single component sphingomyelin bilayers.

J Theor Biol. 1981 Dec 21;93(4):737-55.